Genomic selection and Breeding without Breeding strategy

Date

11. - 15.9. 2017

Venue

Czech University of Life Sciences Prague - University Campus, Prague, Czech Republic

Lecturers

Doc. Ing. Jaroslav Klápště, Ph.D.

Prof. Ing. Milan Lstibůrek, Ph.D.

Ing. Jan Stejskal, Ph.D.

Ing. Jiří Korecký, Ph.D.

Preliminary program

Day 1) Monday

Morning

Arrivals, accommodation
Meeting at 10:30. (Drevarsky pavilon/Building of wood processing, Fakulta lesnicka a drevarska/Faculty of Forestry and Wood Sciences) - point 1 at the map https://mapy.cz/s/1VUxU
The lecture room (DP106) is located in ground floor, near the reception desk
Right after than we will have lunch, so the serious start will be at room DP106 at 12:00

Afternoon

Introduction into genomic selection - Principle description, implementations, current experiences
Factors affecting the accuracy of genomic selection - Definition of factors contributing to the accuracy of genomic selection such as heritability, training population size and an effective number of genomic fragments.

Evening

Day 2) Tuesday

Morning

Genomic data filtering - comparison of different types of genomic data used in forest tree species, their manipulation and filtering
Genomic BLUP - introduction in mixed linear models with emphasis on "animal model", construction of marker-based relationship matrix, cross-validation

Afternoon

Generalized Ridge Regression - introduction into model based on variable selection which is suitable for prediction of phenotypes with mixed inheritance (genetic architecture contains both large and small effect QTLs)
Estimation of additive and non-additive genetic components - construction of marker based additive and non-additive genetic relationship matrices and their implementation in mixed linear models to explore the sources of genetic variance.

Evening

Day 3) Wednesday

Morning

Single-step evaluation - blending pedigree and marker information into single combined relationship matrix to predict breeding values.

Afternoon

Single-step evaluation - blending pedigree and marker information into single combined relationship matrix to predict breeding values.

Evening

Visiting a local brewery (https://www.unetickypivovar.cz/en/) followed by dinner in brewery restaurant

Day 4) Thursday

Morning

Seed orchard designs and software tools (or Genomic selection issues and SO designs on Thursday morning - depending on progress of lectures and interest of participants)

Afternoon

BwB strategy (El-Kassaby and Lstibůrek 2009) - theoretical background, BwB strategy - applications

Evening

Day 5) Friday

Morning

Discussion and conclusion - Challenges of genomic predictions in forest tree species

Afternoon